Neonatology

1.    Neonatal Care.
***) Which of the following might increase fetal lung maturity in preterm delivery:
A.    Estrogen
B.     Prolactin
C.     Thyroxine
D.    Glucocorticoides
E.     Alpha fetoprotein

Answer: D* Glucocorticoides

***) The umbilical stump of the newborn sloughs off after delivery about:
A.    2nd day
B.     5th day
C.     10th day
D.    15th day
E.     21st day

Answer: C* 10th day

***) The tidal volume of a normal newborn is about:
A.    5 ml
B.     20 ml
C.     50 ml
D.    70 ml
E.     120 ml

Answer: B* 20 ml

***) The most common factor associated with neonatal death is:
A.    Birth injury
B.     Prematurity
C.     Congenital malformations
D.    Metabolic diseases
E.     Intrauterine growth restrictions

Answer: B* Prematurity

***) One of the following is associated with small infants:
A.    Mothers with untreated gestational diabetes
B.     Multipara
C.     Large parents
D.    Maternal smoking
E.     Post-date pregnancy

Answer: D* Maternal smoking

***) The fine downy hair covering the skin of a newborn is called:
A.    Vernix caseosa
B.     Lanugo
C.     Milia
D.    Erythema toxicum
E.     Mottling

Answer: B* Lanugo

2.    APGAR score.
***) An infant at birth exhibits pink body with blue extremities, pulse rate of 120/min, lusty cry, limp muscle tone and irregular slow respiration. The Apgar score is:
A.    2
B.     4
C.     6
D.    8
E.     10

Answer: C* 6

***) A newborn baby delivered with peripheral cyanosis, crying well, weak muscle tone, RR = 22/min irregular and HR = 80/min, his Apgar score:
A.    4
B.     5
C.     6
D.    7
E.     8

Answer: C* 6

***) An infant born with good respiration, vigorous cry, heart rate of 105, moving all extremities, body pink and extremities blue. The Apgar score is
A.    10
B.     9
C.     8
D.    7
E.     6

Answer: B* 9

***) All are component of APGAR score, except:
A.    Heart rate
B.     Blood pressure
C.     Respiratory effort
D.    Reflexes
E.     Skin color

Answer: B* Blood pressure

3.    Sepsis in the Neonate.
***) Beta Hemolytic streptococci group A is responsible for all the following except:
A.    Acute glomerulonephritis
B.     Rheumatic fever
C.     Neonatal sepsis
D.    Scarlet fever
E.     Impetigo

Answer: C* Neonatal sepsis

***) All of the following are predisposing factors of neonatal sepsis, except:
A.    Hypothermia
B.     Instrumental delivery
C.     Twins
D.    Amnionitis
E.     Umbilical infection

Answer: C* Twins

***) Predisposing factors for neonatal septicemia include each of the following, except:
A.    Febrile maternal illness
B.     Twins
C.     Frank amnionitis
D.    Umbilical infection
E.     Endotracheal intubation

Answer: B* Twins

4.    Cyanosis.
***) All of the following can cause cyanosis, except:
A.    Renal failure
B.     Congestive heart failure
C.     Polycythemia
D.    Cold
E.     Cor pulmonale

Answer: A* Renal failure

***) A newborn, 12 hours old, cyanosed when he is quiet, becomes pink on crying, the most probable diagnosis is:
A.    Respiratory distress syndrome
B.     Congenital pneumonia
C.     Diaphragmatic hernia
D.    Intracranial hemorrhage
E.     Bilateral choanal atresia

Answer: E* Bilateral choanal atresia

5.    Respiratory Distress.
***) The most likely finding in a neonate with asphyxia is:
A.    Alkalemia
B.     Hypoxia
C.     Hypocapnia
D.    Tachycardia
E.     Increased anal sphincter tone

Answer: C* Hypoxia

***) The features of respiratory distress in newborn are the following, except:
A.    Tachypnea
B.     Flaring of nostrils
C.     Cyanosis
D.    Grunting on expiration
E.     Projectile vomiting

Answer: E* Projectile vomiting

***) Compliance of the lung is increased in which of the following:
A.    Diffuse pulmonary fibrosis
B.     Pleural thickening
C.     Healed tuberculosis with scarring
D.    Emphysema
E.     Hyaline membrane disease

Answer: E* Hyaline membrane disease

***) Regarding hyaline membrane disease all of the following are true, except:
A.    Tachypnea is always present
B.     Affects mainly premature babies
C.     Expiratory grunting is present
D.    The clinical picture will develop within 4-6 hours
E.     Oxygen by mask is the best management

Answer: E* Oxygen by mask is the best management

6.    Diaphragmatic Hernia.
***) The high postoperative mortality for newborn with congenital diaphragmatic hernia is due to:
A.    Increased intra-abdominal pressure
B.     Persistent patent ductus arteriosus
C.     Failure of the collapsed lung to expand
D.    Mediastinal shift with impaired venous return
E.     Abnormal pulmonary microvasculature

Answer: E* Abnormal pulmonary microvasculature

***) An infant is delivered at full term by a spontaneous vaginal delivery to a 29 year old primigravida. At delivery, the infant is noted to have subcostal retractions and cyanosis despite good respiratory effort. The abdomen is scaphoid. On bag and mask ventilation, auscultation of the lungs reveals decreased breath sounds on the left, with heart sounds louder on the right:
A.    Dextrocardia with situs inversus
B.     Diaphragmatic hernia
C.     Pneumonia
D.    Pulmonary hypoplasia
E.     Spontaneous pneumothorax

Answer: B* Diaphragmatic hernia

7.    Hypoglycemia.
***) All the following are associated with hypoglycemia in the newborn, except:
A.    Neonatal asphyxia
B.     Cold stress
C.     Diabetic mother
D.    Sepsis
E.     Rh-incompatibility

Answer: E* Rh-incompatibility

***) All of the following statements are correct about hypoglycemia, except:
A.    It may associate neonatal asphyxia
B.     It may be manifestation of nesidioblastosis
C.     Glucagon and steroids may be used as treatment line
D.    Blood sugar of 45mg% is normal in full term infants
E.     Ketotic hypoglycemia is rare cause of hypoglycemia in childhood

Answer: E* Ketotic hypoglycemia is rare cause of hypoglycemia in childhood

8.    Jaundice.
***) Neonatal jaundice is seen in all the following except:
A.    Breast feeding
B.     Hypothyroidism
C.     Sickle cell disease
D.    Galactosemia
E.     Septicemia

Answer: C* Sickle cell disease

***) Physiological jaundice is characterized by all of the following, except:
A.    Onset after 36 hours of life
B.     Disappears by 10-14 days of life
C.     Associated always with anemia
D.    The total serum bilirubin does not exceed 14 mg%
E.     The direct bilirubin does not exceed 1.5 mg%

Answer: C* Associated always with anemia

***) All of the following are criteria for physiological jaundice, except:
A.    Starts within the first 24 hours
B.     The total serum bilirubin does not exceed 14 mg/dl
C.     The direct bilirubin does not exceed 1.5 mg/dl
D.    It will disappear within 7-10 days in full terms
E.     It does not need treatment by phototherapy

Answer: A* Starts within the first 24 hours

***) In a 12 hours old newborn that has jaundice the roost likely diagnosis of the following is:
A.    Erythroblastosis fetalis
B.     Physiological jaundice
C.     Biliary atresia
D.    Liver enzyme deficiency
E.     Galactosemia

Answer: A* Erythroblastosis fetalis

***) Jaundice appearing in the first day of life suggests one of the following:
A.    Hemolytic disease of the newborn
B.     Hypothyroidism
C.     Bile duct atresia
D.    Breast milk jaundice
E.     Liver enzyme deficiency

Answer: A* Hemolytic disease of the newborn

***) All of the following are causes of neonatal jaundice during the first 24 hours of life, except:
A.    ABO incompatibility
B.     Spherocytosis
C.     Biliary atresia
D.    G6PD deficiency
E.     Rh-incompatibility

Answer: C* Biliary atresia

***) A 2 months old baby is having loose yellow motions after each breastfeeds since birth, body weight is 4.5 kg. The most appropriate action is:
A.    Stop breast feeding and give lactose free formula
B.     Stop breast milk and start WHO solution
C.     Admit to hospital for investigation
D.    Give antidiarrheal medicine
E.     Reassure the mother that her baby is well

Answer: E* Reassure the mother that her baby is well

***) All of the fallowing increases the risk of neonatal jaundice, except:
A.    Prematurity
B.     Trisomy 21
C.     Elective caesarean section
D.    Congenital hypothyroidism
E.     Cephalohematoma

Answer: C* Elective caesarean section

9.    Necrotizing Enterocolitis (NEC).
***) All of the following are predisposing factors for developing necrotizing enterocolitis NEC, except:
A.    Prematurity
B.     Polycythemia
C.     Breast milk feeding
D.    Umbilical catheterization
E.     Perinatal asphyxia

Answer: C* Breast milk feeding

***) Concerning necrotizing enterocolitis all are true, except:
A.    Affects mainly preterm babies
B.     Pneumatosis intestinalis is pathognomonic
C.     It has very good prognosis
D.    Exchange transfusion is a predisposing factor
E.     It may occur during the second or third week of life

Answer: C* It has very good prognosis

10.           Neonatal Skin Conditions.
***) Epstein's pearls on the hard palate of a newborn should be managed with:
A.    Topical antibiotics
B.     Topical steroids
C.     Excision
D.    Hydrogen peroxide
E.     No therapy

Answer: E* No therapy

***) One of the following conditions in the newborn needs immediate management:
A.    Milia
B.     Mongolian blue spots
C.     Intact meningomyelocele
D.    Capillary hemangioma
E.     Erythema toxicum

Answer: C* Intact meningomyelocele

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